Paragon Sports Medicine

Adipose-Derived Cell Therapy in Atlanta

Adipose tissue therapy uses your own fat tissue, prepared and reinjected in a single visit. The tissue is collected through a small mini-liposuction, washed, and mechanically reduced to a smaller particle size, then placed into the treated joint or tendon under ultrasound guidance. It is used in osteoarthritis, chronic tendon injuries and cartilage damage, where the evidence is still developing.

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Abundant Cells.

Powerful Healing.

At Paragon we use your own adipose tissue, which is easier to collect than bone marrow and is harvested through a simple, minimally invasive mini-liposuction. The tissue is washed and mechanically microfragmented. It is not enzymatically digested and no cell population is separated out, so what is reinjected is your own tissue at a reduced particle size with its natural structure intact. Adipose tissue naturally contains stromal cells, pericytes and signalling proteins. Autologous tissue therapies are not FDA approved for the treatment of any orthopedic condition.

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The Science Behind

Adipose Tissue Therapy

What the prepared tissue contains:

Minimally Manipulated Tissue

Adipose tissue is a richer per-volume source of these cells than bone marrow. Reported yields vary widely across published methods, and collection is minimally invasive.

How These Cells Behave

In laboratory studies, cells found in adipose tissue have formed cartilage, bone and tendon cells. What that means for any individual patient is not established.

Potent Growth Factor Release

Adipose tissue naturally contains signalling proteins including VEGF, HGF, IGF-1, bFGF and TGF-β, which are involved in normal tissue repair.

Anti-Inflammatory Modulation

Adipose tissue has been studied for its effect on local inflammation. Results in humans vary and are not established for orthopedic use.

Paracrine Signaling & Tissue Support

Adipose tissue also releases bioactive molecules that take part in normal localrepair signalling.

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Fit middle-aged man with short gray hair wearing a dark gray t-shirt sitting in soft natural light against a plain wall.

Cellular Healing for

Diverse Conditions

Adipose-derived therapy is used for joint degeneration, chronic soft tissue injuries, and inflammatory conditions. Fat tissue is a rich source of mesenchymal cells, and the harvest is less invasive than bone marrow aspiration. It is generally considered where tissue damage is significant, degenerative changes are advanced, or previous treatments have not given lasting relief. Unlike platelet therapies, it delivers mesenchymal cells as well as growth factors. Whether adipose therapy or a platelet-based treatment makes more sense for you is a judgement Dr. Garten will make from your examination and imaging.

Adipose-derived therapy is studied in: Osteoarthritis and joint degeneration, Chronic tendon and ligament injuries, Cartilage defects and soft tissue damage. The evidence in these conditions is still developing and outcomes vary.

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Osteoarthritis & joint degeneration

Knee, hip, shoulder and ankle arthritis, where the aim is to reduce pain and improve function rather than to rebuild cartilage.

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Chronic tendon & ligament injuries

Tennis elbow, Achilles tendinopathy, rotator cuff tears, plantar fasciitis, ligament sprains, and soft tissue injuries.

Muscular man sitting on a bench wearing a black knee brace on his right knee and gray shorts.

Cartilage defects & soft tissue damage

Cartilage loss, meniscal tears, labral tears, and degenerative conditions. These procedures should not be expected to regrow a normal joint.

Your Journey

to Cellular Recovery

01

Harvest Site Preparation

You'll be positioned comfortably for access to the adipose collection site (typically abdomen or flanks). The area is cleaned, sterilized, and local anesthesia is administered to ensure comfort during the mini-liposuction procedure.

02

Adipose Tissue Collection

Using a small cannula, Dr. Garten performs a mini-liposuction to collect adipose tissue. The procedure is well-tolerated under local anesthesia and typically takes 15-20 minutes. Only a small amount of fat is needed (typically 30-60cc).

03

Cellular Processing & Concentration

Your adipose tissue is washed and mechanically reduced to a smaller particle size. It is not enzymatically digested and no cell population is separated out. This takes 30-45 minutes.

04

Ultrasound-Guided Injection

Using real-time musculoskeletal ultrasound, Dr. Garten injects the prepared adipose tissue directly into the treated joint, tendon or ligament.

05

Recovery Protocol

You'll receive activity modification guidelines, recovery strategies, and a phased rehabilitation plan. Follow-up assessments track your progress over subsequent months.

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What to Expect Over the First Six Months

Adipose tissue therapy is not an immediate fix. Any change in pain and function tends to develop gradually over several months. Understanding this timeline helps set realistic expectations.

IMMEDIATE (0-7 DAYS):

Expect mild soreness at the harvest site (abdomen/flanks) with possible bruising or swelling. Most patients describe this as less uncomfortable than expected – similar to post-workout soreness. Injection site may also be tender. Use ice, rest, and prescribed pain management. Avoid NSAIDs as they may interfere with healing.

EARLY PHASE (2-6 WEEKS):

Harvest site discomfort resolves quickly (typically 3-5 days). At the injection site, you may experience temporary increased soreness. This is normal. Gentle movement and progressive activity as tolerated.

WEEKS 6 TO 12:

Most patients who respond notice initial functional improvement during this period as inflammation subsides. Physical therapy typically progresses during this phase.

TISSUE MATURATION (3-6 MONTHS):

Where the treatment helps, improvement in pain and function usually continues through this period, and many patients who respond see their peak improvement here. Not everyone responds.

LONG-TERM (6-12+ MONTHS):

Continued tissue remodeling and functional gains. Full tissue maturation. Some patients continue improving beyond one year, particularly with degenerative conditions. Outcomes depend on severity, age, activity level, and rehabilitation adherence.

ACTIVITY RESTRICTIONS:

  • First week: Limit impact activities, protect harvest and injection sites

  • Weeks 2-6: Gradual return to low-impact activities, structured PT begins

  • Weeks 6-12: Progressive loading, sport-specific training as tolerated

  • 3+ months: Return to full activity based on clinical assessment

Choosing Between the Options

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Adipose vs. BMAC

Key differences: Both use your own tissue, from different sources. Adipose tissue is easier to collect and less uncomfortable to harvest than bone marrow. Bone marrow concentrate has been studied more in bone and cartilage applications. Dr. Garten selects the source based on your condition and goals. Neither is FDA approved for orthopedic conditions.

Adipose vs. PRP

When adipose is preferred: PRP concentrates platelets and growth factors from your blood. Adipose tissue therapy uses your own fat tissue and delivers a different preparation. For many injuries PRP is the appropriate starting point. Neither procedure rebuilds lost cartilage.

Adipose vs. Surgery

Non-surgical alternative: Adipose therapy is delivered as an injection. It does not involve a surgical incision, general anesthesia, or implanted hardware, and it does not close off future surgical options. Some conditions still require surgery, and Dr. Garten will give you an honest assessment of whether adipose therapy is appropriate for yours.

Combination Therapies

Synergistic approach: Adipose tissue therapy is sometimes combined with PRP. Some patients have the two sequentially, others as a combined injection. Dr. Garten designs the plan around the condition.

Your Own Tissue

Adipose tissue is a richer per-volume source of these cells than bone marrow. Reported yields vary widely across published methods, and the cells are collected in a single minimally invasive harvest.

Minimally Invasive Collection

Mini-liposuction under local anesthesia is significantly less invasive and more comfortable than bone marrow aspiration. Most patients experience minimal discomfort during and after harvest, with faster recovery at the collection site.

Potent Growth Factor Profile

Adipose cells release powerful growth factors (VEGF, HGF, IGF-1, bFGF, TGF-β) that promote vascularization, reduce inflammation, stimulate cellular activity, and support comprehensive tissue repair.

Autologous Safety

Because the material is your own tissue, rejection and disease transmission are not concerns. As with any injection, bleeding, infection and pain at the injection and harvest sites remain possible.

Surgical Alternative

For some conditions, adipose tissue therapy is an option worth considering before surgery. It avoids surgical trauma and lengthy rehabilitation, and it does not rule out surgery later. Results vary and not everyone responds.

The Adipose Advantage

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Adipose Therapy:

Your Questions, Answered

How is adipose tissue collected, and is it painful?
How much fat is needed for the procedure?
How is adipose tissue therapy different from bone marrow concentrate?
How long do adipose therapy results last?
How many adipose therapy treatments will I need?
What is the success rate for adipose therapy?
Can adipose therapy help me avoid surgery?
What is the cost of adipose therapy?
Is adipose therapy covered by insurance?
Can adipose therapy be combined with other treatments?
Am I a candidate for adipose therapy?
How is adipose tissue collected, and is it painful?
How much fat is needed for the procedure?
How is adipose tissue therapy different from bone marrow concentrate?
How long do adipose therapy results last?
How many adipose therapy treatments will I need?
What is the success rate for adipose therapy?
Can adipose therapy help me avoid surgery?
What is the cost of adipose therapy?
Is adipose therapy covered by insurance?
Can adipose therapy be combined with other treatments?
Am I a candidate for adipose therapy?

Schedule a

consultation

We treat injuries and we work on what caused them. Whether you're facing joint degeneration or chronic soft tissue damage, our programs combine clinical assessment, current evidence, and carefully selected protocols.Our approach brings together diagnostics, ultrasound-guided delivery, personalized rehabilitation and recovery planning. Progress here isn't accidental — it's planned.

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Adipose and bone marrow derived cell therapies are not FDA approved for the treatment of any orthopedic condition. Their use here is based on clinical judgment and the current published evidence, which is still developing. Individual results vary.

Schedule a

consultation

We treat injuries and we work on what caused them. Whether you're facing joint degeneration or chronic soft tissue damage, our programs combine clinical assessment, current evidence, and carefully selected protocols.Our approach brings together diagnostics, ultrasound-guided delivery, personalized rehabilitation and recovery planning. Progress here isn't accidental — it's planned.

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Adipose and bone marrow derived cell therapies are not FDA approved for the treatment of any orthopedic condition. Their use here is based on clinical judgment and the current published evidence, which is still developing. Individual results vary.