Adipose-Derived Cell Therapy in Atlanta
Adipose tissue therapy uses your own fat tissue, prepared and reinjected in a single visit. The tissue is collected through a small mini-liposuction, washed, and mechanically reduced to a smaller particle size, then placed into the treated joint or tendon under ultrasound guidance. It is used in osteoarthritis, chronic tendon injuries and cartilage damage, where the evidence is still developing.

Abundant Cells.
Powerful Healing.
At Paragon we use your own adipose tissue, which is easier to collect than bone marrow and is harvested through a simple, minimally invasive mini-liposuction. The tissue is washed and mechanically microfragmented. It is not enzymatically digested and no cell population is separated out, so what is reinjected is your own tissue at a reduced particle size with its natural structure intact. Adipose tissue naturally contains stromal cells, pericytes and signalling proteins. Autologous tissue therapies are not FDA approved for the treatment of any orthopedic condition.

The Science Behind
Adipose Tissue Therapy
What the prepared tissue contains:
Minimally Manipulated Tissue
Adipose tissue is a richer per-volume source of these cells than bone marrow. Reported yields vary widely across published methods, and collection is minimally invasive.
How These Cells Behave
In laboratory studies, cells found in adipose tissue have formed cartilage, bone and tendon cells. What that means for any individual patient is not established.
Potent Growth Factor Release
Adipose tissue naturally contains signalling proteins including VEGF, HGF, IGF-1, bFGF and TGF-β, which are involved in normal tissue repair.
Anti-Inflammatory Modulation
Adipose tissue has been studied for its effect on local inflammation. Results in humans vary and are not established for orthopedic use.
Paracrine Signaling & Tissue Support
Adipose tissue also releases bioactive molecules that take part in normal localrepair signalling.


Cellular Healing for
Diverse Conditions
Adipose-derived therapy is used for joint degeneration, chronic soft tissue injuries, and inflammatory conditions. Fat tissue is a rich source of mesenchymal cells, and the harvest is less invasive than bone marrow aspiration. It is generally considered where tissue damage is significant, degenerative changes are advanced, or previous treatments have not given lasting relief. Unlike platelet therapies, it delivers mesenchymal cells as well as growth factors. Whether adipose therapy or a platelet-based treatment makes more sense for you is a judgement Dr. Garten will make from your examination and imaging.
Adipose-derived therapy is studied in: Osteoarthritis and joint degeneration, Chronic tendon and ligament injuries, Cartilage defects and soft tissue damage. The evidence in these conditions is still developing and outcomes vary.

Osteoarthritis & joint degeneration
Knee, hip, shoulder and ankle arthritis, where the aim is to reduce pain and improve function rather than to rebuild cartilage.

Chronic tendon & ligament injuries
Tennis elbow, Achilles tendinopathy, rotator cuff tears, plantar fasciitis, ligament sprains, and soft tissue injuries.
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Cartilage defects & soft tissue damage
Cartilage loss, meniscal tears, labral tears, and degenerative conditions. These procedures should not be expected to regrow a normal joint.
Your Journey
to Cellular Recovery
Harvest Site Preparation
You'll be positioned comfortably for access to the adipose collection site (typically abdomen or flanks). The area is cleaned, sterilized, and local anesthesia is administered to ensure comfort during the mini-liposuction procedure.
Adipose Tissue Collection
Using a small cannula, Dr. Garten performs a mini-liposuction to collect adipose tissue. The procedure is well-tolerated under local anesthesia and typically takes 15-20 minutes. Only a small amount of fat is needed (typically 30-60cc).
Cellular Processing & Concentration
Your adipose tissue is washed and mechanically reduced to a smaller particle size. It is not enzymatically digested and no cell population is separated out. This takes 30-45 minutes.
Ultrasound-Guided Injection
Using real-time musculoskeletal ultrasound, Dr. Garten injects the prepared adipose tissue directly into the treated joint, tendon or ligament.
Recovery Protocol
You'll receive activity modification guidelines, recovery strategies, and a phased rehabilitation plan. Follow-up assessments track your progress over subsequent months.

What to Expect Over the First Six Months
Adipose tissue therapy is not an immediate fix. Any change in pain and function tends to develop gradually over several months. Understanding this timeline helps set realistic expectations.
Precision Expertise. Advanced Cellular Medicine.
Adipose tissue therapy depends on proper harvesting and processing technique. Several factors matter:
With over two decades in regenerative medicine, Dr. Garten performs every adipose procedure under real-time ultrasound guidance.

Choosing Between the Options

Adipose vs. BMAC
Key differences: Both use your own tissue, from different sources. Adipose tissue is easier to collect and less uncomfortable to harvest than bone marrow. Bone marrow concentrate has been studied more in bone and cartilage applications. Dr. Garten selects the source based on your condition and goals. Neither is FDA approved for orthopedic conditions.
Adipose vs. PRP
When adipose is preferred: PRP concentrates platelets and growth factors from your blood. Adipose tissue therapy uses your own fat tissue and delivers a different preparation. For many injuries PRP is the appropriate starting point. Neither procedure rebuilds lost cartilage.
Adipose vs. Surgery
Non-surgical alternative: Adipose therapy is delivered as an injection. It does not involve a surgical incision, general anesthesia, or implanted hardware, and it does not close off future surgical options. Some conditions still require surgery, and Dr. Garten will give you an honest assessment of whether adipose therapy is appropriate for yours.
Combination Therapies
Synergistic approach: Adipose tissue therapy is sometimes combined with PRP. Some patients have the two sequentially, others as a combined injection. Dr. Garten designs the plan around the condition.
Your Own Tissue
Adipose tissue is a richer per-volume source of these cells than bone marrow. Reported yields vary widely across published methods, and the cells are collected in a single minimally invasive harvest.
Minimally Invasive Collection
Mini-liposuction under local anesthesia is significantly less invasive and more comfortable than bone marrow aspiration. Most patients experience minimal discomfort during and after harvest, with faster recovery at the collection site.
Potent Growth Factor Profile
Adipose cells release powerful growth factors (VEGF, HGF, IGF-1, bFGF, TGF-β) that promote vascularization, reduce inflammation, stimulate cellular activity, and support comprehensive tissue repair.
Autologous Safety
Because the material is your own tissue, rejection and disease transmission are not concerns. As with any injection, bleeding, infection and pain at the injection and harvest sites remain possible.
Surgical Alternative
For some conditions, adipose tissue therapy is an option worth considering before surgery. It avoids surgical trauma and lengthy rehabilitation, and it does not rule out surgery later. Results vary and not everyone responds.
The Adipose Advantage

Adipose Therapy:
Your Questions, Answered
Adipose tissue is collected through a mini-liposuction procedure performed under local anesthesia in our office. The harvest site (typically abdomen or flanks) is numbed completely, and most patients report minimal discomfort during the procedure – often describing only pressure or tugging sensations. The procedure takes 15-20 minutes. Afterward, the harvest site may feel sore similar to post-workout muscle soreness, with possible bruising or mild swelling for 3-5 days. Most patients find adipose collection significantly more comfortable than bone marrow aspiration and return to normal activities quickly. Only a small amount of fat is needed (30-60cc), so there's minimal cosmetic change at the harvest site.
Only a small amount of adipose tissue is required – typically 30-60 milliliters (approximately 2-4 tablespoons). This small volume is collected through a tiny incision and causes minimal cosmetic change. Nearly all patients have sufficient adipose tissue for the procedure, regardless of body type. Even individuals with low body fat typically have adequate subcutaneous fat in the abdomen or flanks for a successful harvest.
Both adipose and bone marrow provide mesenchymal cells alongside growth factors, but they differ in several ways. Adipose tissue is a richer per-volume source, with reported yields varying widely across published methods, and collection is less invasive than bone marrow aspiration. The growth factor profiles differ: adipose preparations have been reported to contain higher levels of VEGF and HGF, while bone marrow has been studied more in bone and cartilage settings. What either means for an individual patient is still being studied. Dr. Garten selects the source based on your condition, your imaging and your goals.
Where patients respond, improvement can last, though how long varies with the condition treated and the individual. Many patients experience sustained improvement for multiple years as regenerated tissue functions biologically. Durability depends on condition severity, age, activity level, biomechanics, ongoing degenerative processes, and rehabilitation adherence. Adipose therapy doesn't stop aging or prevent future injury, but regenerated tissue can provide meaningful long-term functional improvement. Some patients may eventually require additional treatment if degeneration progresses, though regenerated tissue often demonstrates better resilience than untreated degenerative tissue. Long-term outcomes continue to be studied as adipose therapy represents evolving advancement in regenerative medicine.
Most patients receive a single adipose treatment to initiate cellular regeneration. Depending on condition severity and initial response, some may benefit from a second treatment 6-12 months later. Unlike PRP series, adipose therapy typically isn't performed repeatedly due to the cellular nature of the treatment and the longer timeline involved. Dr. Garten assesses your response through clinical evaluation and potentially imaging to determine if additional treatment is warranted. Some patients combine initial adipose therapy with subsequent PRP treatments to support the regeneration process without additional fat harvest.
Success rates vary based on the condition treated, severity, patient age, and individual factors. Published outcomes vary widely and no reliable pooled success rate exists. Factors associated with better outcomes include younger age, less severe degeneration, good overall health, appropriate patient selection, and rehabilitation adherence. Adipose therapy tends to be most effective for moderate osteoarthritis, cartilage defects, and chronic tendon injuries where viable tissue remains that can respond to cellular signals. Advanced bone-on-bone arthritis with complete cartilage loss may have lower success rates. Dr. Garten provides realistic expectations based on your specific condition during consultation.
For many patients with moderate-to-severe osteoarthritis, cartilage damage, or chronic tendon tears, adipose therapy is one option some patients consider before surgery. Whether it is appropriate, and what it may achieve, is a clinical decision made after examination and imaging. Success depends on degeneration severity, remaining tissue quality, and individual regenerative capacity. Patients with some remaining cartilage and earlier-stage disease tend to achieve better outcomes. Those with complete cartilage loss or very advanced degeneration may still require surgery, though adipose therapy can be attempted first without compromising future surgical options. Allowing patients to delay surgical intervention.
Adipose therapy costs reflect the specialized procedure, processing equipment, sterile consumables, extended procedure time, and cellular therapy expertise required. Costs vary depending on condition complexity and whether combination therapies are used. Our office provides transparent pricing during consultation. While adipose therapy represents an investment, many patients find it cost-effective compared to ongoing pain management, repeated treatments, or surgical intervention with associated costs and recovery time. We provide documentation for HSA/FSA reimbursement.
Like most regenerative medicine procedures, adipose-derived cell therapy is not typically covered by insurance and is considered out-of-pocket expense. Insurance companies generally classify autologous cellular therapies as investigational despite growing clinical evidence. Our office provides itemized documentation and procedure codes for HSA/FSA accounts or potential partial reimbursement submission, though coverage is not guaranteed. We recommend contacting your insurance provider to inquire about any coverage for autologous adipose-derived cellular procedures.
Yes, adipose therapy is often combined with other regenerative treatments for synergistic effect. Common combinations include:
Adipose + BMAC: Different MSC sources may complement each other for complex conditions
Adipose followed by PRP: Initial adipose for cellular regeneration, then PRP 3-6 months later to support tissue maturation
Adipose + Peptide Therapy: Systemic peptides optimize healing capacity and cellular activity
Adipose + Physical Therapy: Essential for tissue maturation, load tolerance, and functional restoration
Dr. Garten designs personalized treatment protocols that may incorporate multiple modalities to optimize your regenerative outcome.
Ideal candidates typically have moderate-to-severe osteoarthritis, cartilage defects, chronic tendon injuries, or degenerative conditions where cellular regeneration is beneficial and conservative treatments have been insufficient. You may be a good candidate if you have knee/hip/shoulder arthritis with remaining cartilage, tendinopathy or tendon tears, ligament injuries, cartilage damage, or degenerative conditions where conservative care has not worked. You're likely NOT a good candidate if you have active infection, blood clotting disorders, complete bone-on-bone arthritis with severe deformity, unrealistic expectations, or unwillingness to follow extended rehabilitation protocols. Dr. Garten conducts comprehensive evaluation including clinical examination, imaging review, and discussion of goals to determine if adipose therapy is appropriate for your specific situation.
Adipose tissue is collected through a mini-liposuction procedure performed under local anesthesia in our office. The harvest site (typically abdomen or flanks) is numbed completely, and most patients report minimal discomfort during the procedure – often describing only pressure or tugging sensations. The procedure takes 15-20 minutes. Afterward, the harvest site may feel sore similar to post-workout muscle soreness, with possible bruising or mild swelling for 3-5 days. Most patients find adipose collection significantly more comfortable than bone marrow aspiration and return to normal activities quickly. Only a small amount of fat is needed (30-60cc), so there's minimal cosmetic change at the harvest site.
Only a small amount of adipose tissue is required – typically 30-60 milliliters (approximately 2-4 tablespoons). This small volume is collected through a tiny incision and causes minimal cosmetic change. Nearly all patients have sufficient adipose tissue for the procedure, regardless of body type. Even individuals with low body fat typically have adequate subcutaneous fat in the abdomen or flanks for a successful harvest.
Both adipose and bone marrow provide mesenchymal cells alongside growth factors, but they differ in several ways. Adipose tissue is a richer per-volume source, with reported yields varying widely across published methods, and collection is less invasive than bone marrow aspiration. The growth factor profiles differ: adipose preparations have been reported to contain higher levels of VEGF and HGF, while bone marrow has been studied more in bone and cartilage settings. What either means for an individual patient is still being studied. Dr. Garten selects the source based on your condition, your imaging and your goals.
Where patients respond, improvement can last, though how long varies with the condition treated and the individual. Many patients experience sustained improvement for multiple years as regenerated tissue functions biologically. Durability depends on condition severity, age, activity level, biomechanics, ongoing degenerative processes, and rehabilitation adherence. Adipose therapy doesn't stop aging or prevent future injury, but regenerated tissue can provide meaningful long-term functional improvement. Some patients may eventually require additional treatment if degeneration progresses, though regenerated tissue often demonstrates better resilience than untreated degenerative tissue. Long-term outcomes continue to be studied as adipose therapy represents evolving advancement in regenerative medicine.
Most patients receive a single adipose treatment to initiate cellular regeneration. Depending on condition severity and initial response, some may benefit from a second treatment 6-12 months later. Unlike PRP series, adipose therapy typically isn't performed repeatedly due to the cellular nature of the treatment and the longer timeline involved. Dr. Garten assesses your response through clinical evaluation and potentially imaging to determine if additional treatment is warranted. Some patients combine initial adipose therapy with subsequent PRP treatments to support the regeneration process without additional fat harvest.
Success rates vary based on the condition treated, severity, patient age, and individual factors. Published outcomes vary widely and no reliable pooled success rate exists. Factors associated with better outcomes include younger age, less severe degeneration, good overall health, appropriate patient selection, and rehabilitation adherence. Adipose therapy tends to be most effective for moderate osteoarthritis, cartilage defects, and chronic tendon injuries where viable tissue remains that can respond to cellular signals. Advanced bone-on-bone arthritis with complete cartilage loss may have lower success rates. Dr. Garten provides realistic expectations based on your specific condition during consultation.
For many patients with moderate-to-severe osteoarthritis, cartilage damage, or chronic tendon tears, adipose therapy is one option some patients consider before surgery. Whether it is appropriate, and what it may achieve, is a clinical decision made after examination and imaging. Success depends on degeneration severity, remaining tissue quality, and individual regenerative capacity. Patients with some remaining cartilage and earlier-stage disease tend to achieve better outcomes. Those with complete cartilage loss or very advanced degeneration may still require surgery, though adipose therapy can be attempted first without compromising future surgical options. Allowing patients to delay surgical intervention.
Adipose therapy costs reflect the specialized procedure, processing equipment, sterile consumables, extended procedure time, and cellular therapy expertise required. Costs vary depending on condition complexity and whether combination therapies are used. Our office provides transparent pricing during consultation. While adipose therapy represents an investment, many patients find it cost-effective compared to ongoing pain management, repeated treatments, or surgical intervention with associated costs and recovery time. We provide documentation for HSA/FSA reimbursement.
Like most regenerative medicine procedures, adipose-derived cell therapy is not typically covered by insurance and is considered out-of-pocket expense. Insurance companies generally classify autologous cellular therapies as investigational despite growing clinical evidence. Our office provides itemized documentation and procedure codes for HSA/FSA accounts or potential partial reimbursement submission, though coverage is not guaranteed. We recommend contacting your insurance provider to inquire about any coverage for autologous adipose-derived cellular procedures.
Yes, adipose therapy is often combined with other regenerative treatments for synergistic effect. Common combinations include:
Adipose + BMAC: Different MSC sources may complement each other for complex conditions
Adipose followed by PRP: Initial adipose for cellular regeneration, then PRP 3-6 months later to support tissue maturation
Adipose + Peptide Therapy: Systemic peptides optimize healing capacity and cellular activity
Adipose + Physical Therapy: Essential for tissue maturation, load tolerance, and functional restoration
Dr. Garten designs personalized treatment protocols that may incorporate multiple modalities to optimize your regenerative outcome.
Ideal candidates typically have moderate-to-severe osteoarthritis, cartilage defects, chronic tendon injuries, or degenerative conditions where cellular regeneration is beneficial and conservative treatments have been insufficient. You may be a good candidate if you have knee/hip/shoulder arthritis with remaining cartilage, tendinopathy or tendon tears, ligament injuries, cartilage damage, or degenerative conditions where conservative care has not worked. You're likely NOT a good candidate if you have active infection, blood clotting disorders, complete bone-on-bone arthritis with severe deformity, unrealistic expectations, or unwillingness to follow extended rehabilitation protocols. Dr. Garten conducts comprehensive evaluation including clinical examination, imaging review, and discussion of goals to determine if adipose therapy is appropriate for your specific situation.
Schedule a
consultation
We treat injuries and we work on what caused them. Whether you're facing joint degeneration or chronic soft tissue damage, our programs combine clinical assessment, current evidence, and carefully selected protocols.Our approach brings together diagnostics, ultrasound-guided delivery, personalized rehabilitation and recovery planning. Progress here isn't accidental — it's planned.
Adipose and bone marrow derived cell therapies are not FDA approved for the treatment of any orthopedic condition. Their use here is based on clinical judgment and the current published evidence, which is still developing. Individual results vary.
Schedule a
consultation
We treat injuries and we work on what caused them. Whether you're facing joint degeneration or chronic soft tissue damage, our programs combine clinical assessment, current evidence, and carefully selected protocols.Our approach brings together diagnostics, ultrasound-guided delivery, personalized rehabilitation and recovery planning. Progress here isn't accidental — it's planned.
Adipose and bone marrow derived cell therapies are not FDA approved for the treatment of any orthopedic condition. Their use here is based on clinical judgment and the current published evidence, which is still developing. Individual results vary.